Health topic · Metabolic health

Prediabetes and insulin resistance

Prediabetes means blood sugar is higher than usual but not in the diabetes range. Learn how it is detected, why it matters and what lowers the risk of type 2 diabetes.

Written by LON6EVITY Editorial Team · Last updated

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Overview

NIDDK explains that insulin resistance happens when cells respond less well to insulin, so the body needs more of it to keep blood glucose in range. Over time glucose can rise into the prediabetes range.

Why it matters

Prediabetes often has no symptoms. NIDDK notes it raises the risk of type 2 diabetes, heart disease and stroke, which is why it is usually found through blood tests rather than symptoms.

How it is detected

HbA1c and fasting glucose are the tests most commonly used. The USPSTF recommends screening for prediabetes and type 2 diabetes in adults aged 35 to 70 who are overweight or have obesity.

What helps

NIDDK describes weight loss, regular physical activity and healthier eating as effective ways to lower the chance of developing type 2 diabetes.

Factors that can affect the result

  • Excess weight
  • Physical inactivity
  • Family history
  • Age
  • Some medicines

Questions people commonly ask

Does prediabetes always become diabetes?
No. Lifestyle changes can lower the risk, and some people return to normal glucose levels.
Is fasting insulin a standard diagnostic test?
It is not used to diagnose prediabetes in standard guidelines; HbA1c and glucose are.

Related biomarkers

Related tests

Related topics

Understand your biomarkers in context

What does this mean for your own health data? Log your results, follow trends over time and bring an organised summary to your next doctor's appointment.

Sources

  1. Insulin Resistance & Prediabetes. NIDDK.
  2. Prediabetes and Type 2 Diabetes: Screening. USPSTF, 2021.