Do abnormal LFTs always mean liver disease?

No. Results can be affected by exercise, medications and other organs; clinicians look at the overall pattern.

Lab test · Liver

Liver function tests (LFTs)

Liver function tests measure enzymes and proteins such as ALT, AST, ALP, GGT, bilirubin and albumin. Learn what's included and how to prepare.

Written by LON6EVITY Editorial Team · Last updated 2026-09-29

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What the test includes

A liver panel typically includes ALT, AST, alkaline phosphatase (ALP), bilirubin, albumin and total protein; GGT is sometimes added.

Why it's used

MedlinePlus describes liver function tests as a way to check for liver damage or disease and to monitor treatment or medications that can affect the liver.

How to prepare

You may be asked to fast for 10–12 hours. Tell your clinician about medicines and supplements you take.

Questions people commonly ask

Do abnormal LFTs always mean liver disease?: No. Results can be affected by exercise, medications and other organs; clinicians look at the overall pattern.

Related biomarkers

Related tests

Lab testMetabolic panel (BMP / CMP)

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Sources

Liver Function Tests. MedlinePlus, U.S. National Library of Medicine.