Biomarker · Blood count

Hemoglobin

Hemoglobin carries oxygen in red blood cells. What a hemoglobin test measures, what low or high values can point to, and how it fits into a complete blood count.

Written by LON6EVITY Editorial Team · Last updated

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What hemoglobin does

Hemoglobin is the iron-containing protein in red blood cells that carries oxygen from the lungs to the rest of the body and brings carbon dioxide back.

Low and high values

According to MedlinePlus, low hemoglobin can be a sign of anaemia, which may be caused by iron deficiency, vitamin deficiencies, blood loss, or chronic disease. High hemoglobin can occur with lung or heart disease, living at high altitude, smoking or dehydration.

How it is tested

Hemoglobin is usually measured as part of a complete blood count (CBC). If it is low, further tests such as ferritin, vitamin B12 and folate help find the cause.

Reference ranges

Reference ranges differ between laboratories, units and methods, and depend on age, sex and your overall clinical picture. A single result is not a diagnosis — interpret it with a qualified clinician.

Factors that can affect the result

  • Iron status
  • Vitamin B12 and folate
  • Blood loss
  • Altitude
  • Smoking
  • Hydration

Questions people commonly ask

Does low hemoglobin always mean iron deficiency?
No. Iron deficiency is a common cause, but there are others, which is why follow-up tests are used.

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Understand your biomarkers in context

What does this mean for your own health data? Log your results, follow trends over time and bring an organised summary to your next doctor's appointment.

Sources

  1. Hemoglobin Test. MedlinePlus, U.S. National Library of Medicine.
  2. Complete Blood Count (CBC). MedlinePlus, U.S. National Library of Medicine.